Dan,
For what you are doing I would stick with the Canfield 200s you already have (had?) or go to any number of quality heads around the 200 cc range. The AFR 210 would be OK to.
I would not run the AFR 220 unless you are prepared for custom headers and shaft rockers. I ran a set on my old 383 SBC and with standard rockers the valvetrain geometry was less than ideal. I got away with it on a 98% track car. I wouldn't do it on a driver. No off the shelf headers fit. It is a good head, just not the best for your combo.
To make use of the 220 head you need good compression, a big cam with a lot of lift, and spin the motor.
My mismatched 10.31:1 383 SBC combo at 3610 lbs ran a best of 7.37@93+ MPH with a converter that was about 1500 RPM too tight (4000-4200 flash stall). Best 60' was only 1.60. Chassis dynoed at 389 RWHP @ 6800 RPM in 98 deg. heat.
You might look at the Brodix M2 - 215cc head or the Dart Pro 1 - 215 cc head if you need a new head quick and just have to go to a bigger head. The Brodix is good out of the box. The Dart responds very well to porting.
Give Mike Lewis (Wolfplace) a call on the Brodix or Mike Stark @ CFM Performance a call on the Dart.
Good Luck,