Mike, just a couple opinions here, my own!
The cam is a bit on the "big" side for a 10:1 unit, BUT, if you happen to have about 340/350 CFM going in the heads it will "tweak" by!!
One other "but" though, if the car weighs more than your "guess", then you will be somewhat disappointed, I believe!
I say that because we are involved with a '66 SB, T-350, 12 bolt ladder-bar rear and this "ride" tips the scales at 3450 WITHOUT the driver!
Now finally, on the "flip" side, a simple head change later to a 112/114 and you will be in the "ballpark" with the cam choice!
Go with the 300-5 Holley, we have similar 454's (slighty less cam, non-roller, slightly higher compression, 11.25, closed chamber iron heads,) making very close to 625/650 HP with little effort!
Thanks, Gary in N.Y.
P.S. Maybe just elaborate about how the car comes in that posted weight?? Curious!